I only ran into a few lobotomites and a couple of nightstalkers and cyberdogs near the entrance. This is a fairly straight shot, and it doesn’t seem to be too dangerous of a walk along the way. Also, if you let to scavenge, note that there are tons of cigarettes inside the lab, so it may be worth it to leave some extra space for the cartons. Unlocking the sonic emitter’s ability to break these will let you loot more effectively as you explore the Big Empty.
This is a good one to do quickly, as several of the other research labs are locked off with force fields.